Cutis marmorata telangiectatica congenita is characterized by reticular erythema that is either generalized over the entire body or localized to a specific area or. Cutis marmorata telangiectatica congenita (CMTC) is a rare condition that causes a marbled pattern on the skin. Learn the symptoms, other. Cutis marmorata telangiectatica congenita. Authoritative facts about the skin from DermNet New Zealand Trust.

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Rarely, Adams-Oliver and Proteus -like syndromes underlie the vascular abnormalities. Facial involvement is very rare. However, several members of a family may occasionally have CMTC.

Rare Disease Database

Health care resources for this disease Expert centres 56 Diagnostic tests 1 Patient organisations 6 Orphan drug s 0. The team brings the expertise of other Boston Children’s departments and services as necessary to provide your child with the best care.

One child had triventricular hydrocephalus without functional complaints.

Specialised Social Services Eurordis directory. Hypotheses that have been proposed include: When the skin is warmed the condition disappears.

His electroencephalogram was abnormal, with erratic disturbances demonstrated only once. She also had extensive tleangiectatica abnormalities, including hypertelorism, brittle hair, low-set ears, a flat face, and small teeth.

Standard ophthalmologic examination in all cases of CMTC seems unnecessary and should be limited to the cases in which there are vascular lesions around the eyes.


Cutis marmorata telangiectatica congenita

The skin symptoms associated with classical CMTC improve with age and usually disappear completely around puberty. Suffolk, VA Phone: Histological examination of a biopsy may show an increase in the number and size of capillaries and veins rarely lymphaticsdilated capillaries located in the deeper dermis, and hyperplasia and swollen endothelial cells with occasional dilated veins and venous lakes.

These are not always regarded as associated anomalies, but teelangiectatica included in the specific skin findings in CMTC. Two other patients were each dizygotic twins, but in both cases the other twin had no signs of CMTC or any other vascular skin lesion.

Cutis marmorata telangiectatica congenita: People with visible marks generally feel fine physically and can act normally, but when it is mentioned, they may become withdrawn and self-conscious. We studied the medical records of 35 patients who were seen at the Pediatric Dermatology Unit of the Sophia Children’s Hospital in Rotterdam, the Netherlands, between July and February Her head circumference was at the 50th mamrorata.

The colour of the lesion can range from deep violet to red. Adams—Oliver syndrome and phakomatosis pigmentovascularis.

Cutis marmorata telangiectatica congenita is characterized by reticular erythema that is either generalized over the entire body or localized to a specific area or limb. Other than 1 boy with hyperplasia of his left cheek, all patients with body asymmetry had hypoplasia or hyperplasia of an extremity.


For accurate diagnosis of cutis marmorata telangiectatica congenita, several disorders must be ruled out Box 1. Indian Dermatol Online J.

Orphanet: Cutis marmorata telangiectatica congenita

Although its course is variable, the majority of lesions in mild cases fade by adolescence. A difference in circumference was observed in 6 cases, in length in 2 cases, and in both circumference and in length in 7 cases.

The most common association of true CMTC is with soft tissue marmoraat fat and muscle hypoplasia. All studies receiving U. Sign in to save your search Sign in to your personal account. Prognosis Prognosis is generally good, with a tendency for clinical improvement during infancy or even complete resolution. Notes Blog Read clinical updates and the latest insights from Boston Children’s specialists. This anomaly has been described in the literature by a number of authors.

Hence, the erythema may be worsened by cooling, physical activity, or crying. Please review our privacy policy.